Interleukin-10: A Pleiotropic Regulator in Pregnancy
نویسندگان
چکیده
منابع مشابه
Significant roles played by interleukin-10 in outcome of pregnancy
Imbalanced immune responses against fetus alloantigens can lead to abnormality in pregnancy. Interleukin-10(IL-10) plays key roles in regulation of immune responses against self and foreign antigens to induce tolerance to these antigens. Therefore, alteration in expression of IL-10 during pregnancy may result in several pathologic conditions such as preterm labor. IL-10 leads to a normal pregna...
متن کاملsignificant roles played by interleukin-10 in outcome of pregnancy
imbalanced immune responses against fetus alloantigens can lead to abnormality in pregnancy. interleukin-10(il-10) plays key roles in regulation of immune responses against self and foreign antigens to induce tolerance to these antigens. therefore, alteration in expression of il-10 during pregnancy may result in several pathologic conditions such as preterm labor. il-10 leads to a normal pregna...
متن کاملSignificant roles played by interleukin-10 in outcome of pregnancy
Imbalanced immune responses against fetus alloantigens can lead to abnormality in pregnancy. Interleukin-10 (IL-10) plays key roles in regulation of immune responses against self and foreign antigens to induce tolerance to these antigens. Therefore, alteration in expression of IL-10 during pregnancy may result in several pathologic conditions such as preterm labor. IL-10 leads to a normal pregn...
متن کاملinterleukin-6 and interleukin-10 gene polymorphisms and recurrent pregnancy loss in romanian population
background: approximately 10-14% of the clinically acknowledged pregnancies end with spontaneous abortion at caucasian population. possible immunologic causes of recurrent miscarriages have been extensively researched. the change in the cytokines balance synthesis in favor of those synthesized by th2 cells with an increase of interleukin 6 (il6) and interleukin10 (il10) secretion is considered ...
متن کاملInterleukin-6: discovery of a pleiotropic cytokine
In the late 1960s, the essential role played by T cells in antibody production was reported. This led to our hypothesis that certain molecules would have to be released from T cells to effect the stimulation of B cells. This hypothesis was shown to be true. There were certain factors present in the culture supernatant of T cells that induced proliferation and differentiation of B cells. The fac...
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ژورنال
عنوان ژورنال: American Journal of Reproductive Immunology
سال: 2014
ISSN: 1046-7408
DOI: 10.1111/aji.12329